Symbol
Name
ID

Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
MGI:104781

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Mouse Phenotypes

increased susceptibility to pharmacologically induced seizures

environmentally induced seizures

tonic-clonic seizures

abnormal nervous system morphology

abnormal cerebellum development

abnormal cerebellar lobule formation

abnormal cerebellum external granule cell layer morphology

abnormal substantia nigra pars compacta morphology

abnormal cochlear VIII nucleus morphology

abnormal hippocampal mossy fiber morphology

abnormal hippocampus pyramidal cell layer

ectopic hippocampus pyramidal cells

abnormal cerebellum morphology

abnormal cerebellar cortex morphology

abnormal cerebellar Purkinje cell layer

abnormal Purkinje cell morphology

abnormal Purkinje cell dendrite morphology

decreased Purkinje cell number

increased Purkinje cell number

ectopic Purkinje cell

delaminated Purkinje cell layer

abnormal cerebellar granule layer morphology

abnormal cerebellar granule cell morphology

thin cerebellar granule layer

abnormal cerebellar molecular layer

absent cerebellum fissure

absent cerebellar lobules

abnormal cerebellum vermis morphology

small cerebellum

decreased dopaminergic neuron number

abnormal nervous system electrophysiology

abnormal synaptic transmission

abnormal CNS synaptic transmission

abnormal synaptic glutamate release

abnormal synaptic neurotransmitter level

Availability

Mouse Genotype

Kcnj6^tm1Stf/Kcnj6^tm1Stf

Kcnj6^wv/Kcnj6^wv

Kcnj6^tm1Stf/Kcnj6^wv

Kcnj6^wv/Kcnj6⁺

Kcnj6^em1.1Ktaka/Kcnj6^em1.1Ktaka
Slc6a3^{tm1.1(cre)Bkmn}/Slc6a3⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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